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AMGNSubstantive discussion · 3/5Save idea

Amgen commercializes Stowers osteoporosis discovery

The guest highlighted a successful research monetization pathway where the Stowers Institute discovered a biological mechanism to reverse osteoporosis and sold the technology to Amgen.

The argument

The guest discussed how the non-profit Stowers Institute for Medical Research, funded by asset management firm American Century, collaborates with and sells discoveries to commercial pharmaceutical companies. Specifically, they discovered a mechanism in fish that not only slows but reverses osteoporosis, which was subsequently acquired and commercialized by Amgen.

The thesis, stress-tested
✓ What validates it
  • Clinical trial data updates or revenue milestones reported by Amgen regarding its osteoporosis treatments
▸ Risks discussed
  • Clinical development and regulatory approval risks for licensed compounds
  • Dependence on basic science discoveries translating to human biology
Hear it yourself
"American Century is a Kansas City based asset manager with over 300,000,000,000 in assets whose ownership structure directs much of its profits to the Stowers Institute for Medical Research."
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AMGN: Amgen commercializes Stowers osteoporosis discovery · Zortix